Matrix effect, signal suppression and enhancement in LC–ESI–MS
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چکیده
منابع مشابه
Overcoming matrix effects in liquid chromatography-mass spectrometry.
A major limitation in quantitative analysis with electrospray ionization mass spectrometry (ESI-MS) is represented by the so-called matrix effects in which the matrix coextracted with the analytes can alter the signal response, causing either suppression or enhancement, resulting in poor analytical accuracy, linearity, and reproducibility. In the direct electron ionization liquid chromatography...
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تاریخ انتشار 2011